| Mile | Eastbound | Westbound |
|---|---|---|
| 0.0 | Interstate Begins | Interstate Ends |
| 0.3 | Exit 1 Binghamton | |
| 2.1 | Exit 2 Chenango Bridge | Exit 2 Chenango Bridge |
| 4.3 | Exit 3 Port Crane | Exit 3 Port Crane |
| 7.7 | Exit 4 Sanitaria Springs | Exit 4 Sanitaria Springs |
| 11.7 | Exit 5 Martin Hill Road Belden | Exit 5 Martin Hill Road Belden |
| 15.7 | Exit 6 Harpursville Nineveh | Exit 6 Harpursville Nineveh |
| County Line Broome / Chenango County Line | County Line Broome / Chenango County Line |